4 replies to this topic

[limpa1982]

I a new to micro RNA research. I have some questions regarding its nomenclature. If I have miRNA-148 is it same as miRNA-148a, miRNA-148b, miRNA-148ab? are any of these similar to each other?

[pcrman]

You can take a look at the help page of miRBASE. miRNA nomencalutre is evolving, you should read several of the papers listed on that page.

[Tabaluga]

pcrman, on 06 January 2013 - 11:21 PM, said:

You can take a look at the help page of miRBASE http://www.mirbase.o...lp/index.shtml. miRNA nomencalutre is evolving, you should read several papers listed on that page..

Hi pcrman, I think this link doesn't work (am also interested in the subject Guess you meant that: http://www.mirbase.o...enclature.shtml
"Lettered suffixes denote closely related mature sequences -- for example hsa-miR-121a and hsa-miR-121b would be expressed from precursors hsa-mir-121a and hsa-mir-121b respectively."
Also found this: http://www.mirbase.o...hats-in-a-name/

Edited by Tabaluga, 06 January 2013 - 11:59 PM.

[pcrman]

http://rnajournal.cs...nt/9/3/277.full

"Identical or very similar miRNA sequences within a species can also be given the same number, with their genes distinguished by letter and/or numeral suffixes, according to the convention of the organism (e.g., the ∼22-nt transcripts of Drosophila mir-13a and mir-13b are slightly different in sequence, whereas those of mir-6-1 and mir-6-2 are identical)

[limpa1982]

thanks guys.
I want to find out if any of these are same.

miR-200bc and miR-200a and miR-200b

Any of these 3 are same? When it is written miR-200bc, does that mean it is miR-200b and c both?