Jump to content

  • Log in with Facebook Log in with Twitter Log in with Windows Live Log In with Google      Sign In   
  • Create Account

Submit your paper to J Biol Methods today!
Photo
- - - - -

MicroRNA nomenclature


  • Please log in to reply
4 replies to this topic

#1 limpa1982

limpa1982

    member

  • Members
  • Pip
  • 2 posts
0
Neutral

Posted 06 January 2013 - 05:00 PM

I a new to micro RNA research. I have some questions regarding its nomenclature. If I have miRNA-148 is it same as miRNA-148a, miRNA-148b, miRNA-148ab? are any of these similar to each other?

#2 pcrman

pcrman

    Epigenetist

  • Global Moderators
  • PipPipPipPipPipPipPipPipPipPip
  • 1,165 posts
67
Excellent

Posted 06 January 2013 - 11:21 PM

You can take a look at the help page of miRBASE. miRNA nomencalutre is evolving, you should read several of the papers listed on that page.

#3 Tabaluga

Tabaluga

    Making glass out of shards

  • Active Members
  • PipPipPipPipPipPipPipPipPipPip
  • 362 posts
47
Excellent

Posted 06 January 2013 - 11:56 PM

You can take a look at the help page of miRBASE http://www.mirbase.o...lp/index.shtml. miRNA nomencalutre is evolving, you should read several papers listed on that page..


Hi pcrman, I think this link doesn't work (am also interested in the subject Posted Image Guess you meant that: http://www.mirbase.o...enclature.shtml
"Lettered suffixes denote closely related mature sequences -- for example hsa-miR-121a and hsa-miR-121b would be expressed from precursors hsa-mir-121a and hsa-mir-121b respectively."
Also found this: http://www.mirbase.o...hats-in-a-name/

Edited by Tabaluga, 06 January 2013 - 11:59 PM.

Il dort. Quoique le sort fût pour lui bien étrange,
Il vivait. Il mourut quand il n'eut plus son ange;
La chose simplement d'elle-même arriva,
Comme la nuit se fait lorsque le jour s'en va.

 


#4 pcrman

pcrman

    Epigenetist

  • Global Moderators
  • PipPipPipPipPipPipPipPipPipPip
  • 1,165 posts
67
Excellent

Posted 07 January 2013 - 05:11 AM

http://rnajournal.cs...nt/9/3/277.full

"Identical or very similar miRNA sequences within a species can also be given the same number, with their genes distinguished by letter and/or numeral suffixes, according to the convention of the organism (e.g., the ∼22-nt transcripts of Drosophila mir-13a and mir-13b are slightly different in sequence, whereas those of mir-6-1 and mir-6-2 are identical)

#5 limpa1982

limpa1982

    member

  • Members
  • Pip
  • 2 posts
0
Neutral

Posted 08 January 2013 - 09:59 AM

thanks guys.
I want to find out if any of these are same.

miR-200bc and miR-200a and miR-200b

Any of these 3 are same? When it is written miR-200bc, does that mean it is miR-200b and c both?




Home - About - Terms of Service - Privacy - Contact Us

©1999-2013 Protocol Online, All rights reserved.