Antibodies against protein complexIs it poosible to raise?
Posted 27 December 2012 - 10:26 PM
Posted 28 December 2012 - 02:15 AM
if you immunize with a complex of proteins you will raise a polyclonal response. Given that some epitopes are immuno-dominant compared to others, most probably the result will be that you get antibodies to only a few of the proteins of your complex. I have done this several times with that results; there is also publications confirming this results. Hope this helps!
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Posted 28 December 2012 - 03:03 AM
Posted 10 January 2013 - 03:02 AM