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Help explaining very long exons in a dataset.


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#1 cam92

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Posted 05 December 2012 - 01:55 PM

I'm looking at a dataset which contains all exon information for chromosomes 3 and 4 (human). Some exons appear to be very long. We've been asked to explain why this is so and if these are really exons. Is there a biological reason why there would be exons that are much longer than we would expect or is this a product of the sequencing technology?

Thanks for any help.

#2 pcrman

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Posted 05 December 2012 - 06:54 PM

Do you know how the dataset was generated-- RNA seq, exon seq or genome seq?

#3 cam92

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Posted 06 December 2012 - 12:18 AM

I think it is genome sequencing. Though I could be wrong, all the question states is that they generated a table with all the exons in the human genome. It compares them to exons of people with diseases and this data was obtained with exon sequencing.

Edited by cam92, 06 December 2012 - 03:58 AM.





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