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What's the best way to prove c-Abl activation/inhibition?

c-Abl phospho-antibody

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#1 Brad Ruan

Brad Ruan

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Posted 09 November 2012 - 08:47 AM

I'm trying to detect whether the c-Abl protein in my cell lines are inhibited upon drug treatment. What is the best way to prove that? I think using the GST-Crk substrate is too much effort. Can I use phospho-c-Abl antibody? Which one is better? The pTyr245 or pTyr412? Thanks for helping!




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