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silent mutations


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#1 spidermanforever

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Posted 05 October 2012 - 02:20 AM

Is there any way in which this type of mutation can change the phenotype of an individual....

Edited by spidermanforever, 05 October 2012 - 02:20 AM.


#2 metionina

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Posted 05 October 2012 - 04:01 AM

I think yes.
A silent mutation in a gene doesn't change the amino acid of the protein, but you have to consider also the regulation mechanisms associated with the gene (the mutation may cause for example a different splicing or a different regulation of the expression of the gene).
Maybe you can look for some examples in pubmed.

#3 spidermanforever

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Posted 05 October 2012 - 07:12 AM

I have tried looking on the net but cannot find any examples :(

#4 metionina

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Posted 05 October 2012 - 07:27 AM

some examples found in pubmed
http://www.ncbi.nlm....pubmed/17001296
http://www.ncbi.nlm....pubmed/10775534
http://www.ncbi.nlm..../pubmed/9197418

and more general articles
http://www.nature.co...s061218-12.html
http://seedmagazine....und_of_silence/




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