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fold change (how to represent it)


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#1 vitalgene

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Posted 08 September 2012 - 11:39 AM

I was wondering how to represent fold change for qPCR data. Should it be log scale or linear scale.
I saw some paper showing data a fold increase (or decrease) of mRNA. Lets say the control value is 1 and the treatment cause it to go down say 0.259, what will be the right way of representation; and also if the treatment value is 4.
thank you in advance
vg

#2 bob1

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Posted 08 September 2012 - 08:50 PM

The easiest way is to plot a graph with the X axis on no change then draw bars above and below for +/- change respectively. Like figure 9 here




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