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what will happen if you let your affinity column beads dry?

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#1 rock&science



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Posted 07 August 2012 - 10:16 PM

does anyone know what will really happen? I know that it's going to wreck the column, but what does actually happen? thanks

Edited by rock&science, 07 August 2012 - 10:16 PM.

#2 mdfenko


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Posted 09 August 2012 - 12:18 PM

depends on the beads...

can cause breakage leading to "fines" which will interfere with the flow of mobile phase (the technical term is "clog the column")
talent does what it can
genius does what it must
i do what i get paid to do

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