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cell line syngeneic with mouse mdel


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#1 SF_HK

SF_HK

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Posted 02 August 2012 - 02:16 PM

Hi, I'm new to the area of animal studies.  What is the meaning of: a cell line in syngeneic with the a particular breed of mice?
I read a paper which states that: MC-38 colon cancer cell line, which is syngeneic with the C57BL/6 background.

I have to develop xenograft orthotopic mouse model. How do I choose which mouse model to use with which cell line?




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