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How can we do the randomization for a clinical study in a population

randomization clinical study sample size population

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#1 srimadh



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Posted 27 June 2012 - 09:11 PM

Hi all,

I am a fresher, just started my PhD in Immunogenetics. I am planning to take up a clinical study on a population for certain autoimmune diseases.

I was suggested that before I proceed with my clinical study, I should be clear as to what can be my sample size, how do I select the sample ... it was suggested that I should randomize the sample population. Here I need some assistance as to how we can go about randomization of the sample population ...

I would like to know the process how it is done ...say for a given population.

Please help me through this. Posted Image

Thank you.

#2 bob1


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Posted 28 June 2012 - 01:59 PM

It depends on the type of study. If you were doing a drug trial for instance, you should do a double blind of the treatments (both doctor/person handing over the drugs and patient know who is getting drug and who control). For other types you might have a number of patients with the same diagnosed condition and you randomly sample from that population - talk to a statistician, they will be able to help design this well.

You should also discuss with your supervisor - they will know how to go about this and any regulations you need to follow.

Also in the end remember that these are people, and patient samples are precious, don't annoy your patients and don't waste samples!

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