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How to present microarray data of two samples?

microarray microRNA gene expression

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#1 kaveh



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Posted 09 May 2012 - 07:21 PM

I have a microRNA-microarray data of two genotypes (control vs. experiment). The array has 150 probes and in my experiment there are only 45 of them being expressed. Out of that, there is only one differentially expressed microRNA (SAM analysis). What is the best way to present this data in a publication? I know that people use heat-map when they have more than two samples. But what if you have only two?

I can think about two possibilities:

1) Having a bar graph that shows all the 45 expressed microRNas and they're corresponding fold change (like this). Then putting an asterisk on the significant bar.

2) Using the SAM graph (expected vs. observed) and marking the microRNA that is not within the confidence limits (like this).

any input is highly appreciated.

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