Jump to content

  • Log in with Facebook Log in with Twitter Log in with Windows Live Log In with Google      Sign In   
  • Create Account

Submit your paper to J Biol Methods today!
Photo

miRZIP technology


  • Please log in to reply
No replies to this topic

#1 Shifting Reality

Shifting Reality

    member

  • Active Members
  • Pip
  • 14 posts
0
Neutral

Posted 03 May 2012 - 12:59 AM

Hello :)

miRZiP anti-sense microRNAs are stably expressed RNAi hairpins that have anti-microRNA activity.The
miRZip shRNAs produce short, single-stranded anti-microRNAs that competitively bind their endogenous
microRNA target and inhibit its function. Because these are short hairpins, I assume that a hairpin was processed by the Dicer so the anti-sense strand can incorporate to the RISC complex. Does anybody know that how the anti-sense strand can bind to its target miRNA if the anti-sense strand can be found in the RISC complex?

SF




Home - About - Terms of Service - Privacy - Contact Us

©1999-2013 Protocol Online, All rights reserved.