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A question about mRNA


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#1 zhenghj

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Posted 17 June 2003 - 08:14 PM

I want to know ,when the content of a kind of antibody reaches the highest level
in the body, does it mean that the mRNA expressed it had reached the highest
level either?

#2 bonesj

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Posted 13 July 2003 - 05:32 AM

There is a direct correlation to mRNA levels and antibody production. This is the basis for the newest wave of molecular based immunoassays (RealTime-PCR, etc) that are focusing on autoimmune responses. It is not a safe assumption, however, to say that a maximum production of antibody is only limited by the mRNA that encodes it. Unfortunately, life's never that simple ;)

There are other cell functions and possible limiting components that can effect the level of antibody production.

Jen




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