Our lab already has a set of Coorstek ceremic mortar and pestle. However, the lab manager appeared to have some concerns about its porosity (and by extension hard to decontaminate).
So, for those who routinely grind tissues with mortar and pestles for RNA:
- Is the porosity of ceremic mortar and pestle an actual concern for RNA extraction?
- If it is a concern, does that mean we have to buy the more expensive agate or AlO2 mortar and pestles?
- How do you decontaminate mortar and pestle between tissues? We may need to do several of them in a row.