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Nicotinamide (NAM)- Inhibitor of Sirtuins

Started by Shin Yee, Jan 05 2012 05:46 AM

Metabolism sirtuin sirt nicotinamide nam

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#1 Shin Yee

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Posted 05 January 2012 - 05:46 AM

Hi all

Have anyone of you used nicotinamide before to inhibit sirt? it is a common inhibitor for sirtuins however there is no effect when i treat them in HEK293T cells. What concentration should i use and how long should i treat?