0
2 replies to this topic
#1
john909
-
- Members
-
- 1 posts
member
0
Neutral
Neutral
Posted 01 November 2011 - 04:00 PM
I have a quick question. I'm having difficulty understanding why non specificity in ligand binding experiments is desired to be kept to a minimum. What are the disadvantages of having an experiment which results in high non specific radioligand binding?
thanks for your time
John
#2
leelee
-
- Active Members
-
- 644 posts
Veteran
51
Excellent
Excellent
Posted 01 November 2011 - 07:13 PM
Ok well think about it, if you are using a radioligand to measure/detect/visualise a specific receptor- what use is it if it binds to something other than what you are interested in?
#3
mdfenko
-
- Active Members
-
- 2,292 posts
an elder
84
Excellent
Excellent
Posted 03 November 2011 - 05:51 AM
think "background" and signal to noise ratio
talent does what it can
genius does what it must
i do what i get paid to do
genius does what it must
i do what i get paid to do
