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[Chris Szeto]

I've been analysing my data using Biacore T100 biaevaluation software. Might be an old version installed in the lab's PC (v 1.1.1?) and I can't seem to be able to align the injection points across different flow cells, making my sensorgrams contain strange dips and spikes which affects the fit curves for kinetic values.

I've done a search and have come across scrubber 2, which has a tonne of useful tools to fix up your data including realigning injection points and also allows the subtraction of blank injections. The demo allows you to do all of this, but doesn't put out any values (it's a demo after all). There's also no price stated for registration.

Just wanted to ask (before I decide to ask my supervisor to purchase a license) if anyone has come across any good open-source/free-to-use SPR analysis software, or if these things are available for updated versions of Biacore's biaevaluation software?

This is the scrubbed version:





This is Biacore's Biaevaluation v1.1.1