Jump to content

  • Log in with Facebook Log in with Twitter Log in with Windows Live Log In with Google      Sign In   
  • Create Account

Submit your paper to J Biol Methods today!
- - - - -

Microarray data bimodal distribution of intenstiy values

  • Please log in to reply
No replies to this topic

#1 rachgibson



  • Members
  • Pip
  • 1 posts

Posted 06 May 2011 - 04:12 AM

Hi there

I was wondering if anyone could please give me some advice, I have two independent sets of microarray data which are Agilent one colour for gene expression. My plan was to compare Wildtype to mutant expression profiles. I am having major problems as all samples, mutant and the wildtype, show a bimodal distribution of intensity. I was wondering if anyone else has experienced this and has any advice? I am new to microarrays and completely lost? The data is not normally distributed so am unable to use conventional modelling/ bioinformatic resources like babelomics as all assume a normal distribution.

Any advice would be greatly appreciated


Home - About - Terms of Service - Privacy - Contact Us

©1999-2013 Protocol Online, All rights reserved.