I am looking for proteins that you wanted to express but it failed because the protein contained a (globular) domain and the protein aggregated. Usually such proteins/experiments won't be published by their very nature. However, we are collecting such proteins/domains to test our server that would predict exactly such events. Could you please, send me your misbehaving protein or if you know about such a failed experiment, that would be great, too. Please, let me know! Here is our paper about the background: http://www.ncbi.nlm....pubmed/20972208 We are developing now a server and if you could send a valid example (either positive or negative), we'd be happy to acknowledge it in our upcoming paper about the server. Thanks, H.Hegyi
You have truncated protein domain that won't express?
Started by drckitty, May 01 2011 01:49 PM
1 reply to this topic
#1
Posted 01 May 2011 - 01:49 PM
#2
Posted 01 May 2011 - 01:54 PM
In case I was ambiguous in my previous post: we are looking for proteins with TRUNCATED globular domain(s) where the protein aggregation was probably caused by the domain truncation.
Your failed protein expression would be greatly appreciated (and probably I am the only one who'd be interested in such a failed experiment).
Thanks,
H.Hegyi
In case
Your failed protein expression would be greatly appreciated (and probably I am the only one who'd be interested in such a failed experiment).
Thanks,
H.Hegyi
drckitty, on 01 May 2011 - 01:49 PM, said:
I am looking for proteins that you wanted to express but it failed because the protein contained a (globular) domain and the protein aggregated. Usually such proteins/experiments won't be published by their very nature. However, we are collecting such proteins/domains to test our server that would predict exactly such events. Could you please, send me your misbehaving protein or if you know about such a failed experiment, that would be great, too. Please, let me know! Here is our paper about the background: http://www.ncbi.nlm....pubmed/20972208 We are developing now a server and if you could send a valid example (either positive or negative), we'd be happy to acknowledge it in our upcoming paper about the server. Thanks, H.Hegyi
In case













