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Opinions wanted - What is needed to design enzymes capable of the rate enhanceme


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4 replies to this topic

#1 jerseysurfer66

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Posted 24 April 2011 - 10:36 AM

Wanted discussions on how enzymes reach 10^16+ rate increases and what can be done to design enzymes with similar rate increases.

I'll start the discussion by saying that I don't believe transition state stabilization results in the bulk of the rate increase in enzyme catalysis.

#2 Kaioshin

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Posted 24 April 2011 - 06:54 PM

Wanted discussions on how enzymes reach 10^16+ rate increases and what can be done to design enzymes with similar rate increases.

I'll start the discussion by saying that I don't believe transition state stabilization results in the bulk of the rate increase in enzyme catalysis.


How can we design our own enzymes?
For starters, we need to gather ~1 trillion more years in man hours worth of research...

#3 jerseysurfer66

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Posted 24 April 2011 - 07:23 PM

Agree on that we need much more research but highly doubtful a trillion years is necessary. This is a next 10 year development.

#4 Kaioshin

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Posted 26 April 2011 - 05:30 AM

Agree on that we need much more research but highly doubtful a trillion years is necessary. This is a next 10 year development.


You should probably look up the definition of "man hours"

#5 jerseysurfer66

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Posted 26 April 2011 - 05:54 AM

U should try and understand the number "a trillion" .




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