What is the purpose of protease inhibitors and proteasome inhibitors?
Obviously by the name, its obvious to say its an inhibitor, but looking at the big picture, what is its purpose?
0
2 replies to this topic
#2
mdfenko
-
- Active Members
-
- 2,288 posts
an elder
83
Excellent
Excellent
Posted 14 February 2011 - 02:20 PM
to prevent your protein of interest from being degraded by the proteases/proteasomes during purification.
talent does what it can
genius does what it must
i do what i get paid to do
genius does what it must
i do what i get paid to do
#3
ken_zhang
-
- Active Members
-
- 11 posts
member
0
Neutral
Neutral
Posted 16 February 2011 - 10:05 PM
Biochem_newbie, on 14 February 2011 - 10:57 AM, said:
What is the purpose of protease inhibitors and proteasome inhibitors?
Obviously by the name, its obvious to say its an inhibitor, but looking at the big picture, what is its purpose?
Obviously by the name, its obvious to say its an inhibitor, but looking at the big picture, what is its purpose?
In my opinion,most protease inhibitors are small molecule compound.We use those small molecule compound to prevent the degradation of our target protein beacuse the enzymes in vivo may degrade many proteins including our targeting when cells are broken.Proteasome inhibitors are one kind of protease inhibitors.
