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secretory protein


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#1 SF_HK

SF_HK

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Posted 30 January 2011 - 07:09 AM

Hi

Is it heard of to find secretpry proteins to be localised in the nucleus? My protein of interest is secretory and binds to a receptor on the cell surface but upon IHC, I find it localised in the nuclaus and weak staining in the cytoplasm.

The anibody is polyclonal but gives a right size band on western. Plus, cytoplasmic and nuclear fractions show strong localization in the nuclear fraction upon western.




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