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Voltage clamp for AMPAR and NMDAR


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#1 patric star

patric star

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Posted 23 December 2010 - 07:20 AM

Could anyone help me figure out why we usually set holding potential at about -70mV and +40mV while recording AMPAR and NMDAR-mediated synapse currents, respectively?

and why usually NMDAR shows upward deflection, yet AMPAR shows downward? what do upward and downward mean?

thx for your kind help ! :rolleyes:




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