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why do macrophages detach with lidocaine ?


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#1 celbio

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Posted 12 July 2002 - 12:58 AM

Dear fellow researchers

We are currently using lidocaine to detach our macrophages from the petri dish.
But we havn't got a clue about the mechanisms of detachment and whether it has any other effects irreversible on the function of our macrophages.

does anybody know the answer to our question ?

Greeting Edwin And Ester


#2 alloyd

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Posted 16 July 2002 - 10:33 AM

The lidocaine changes the shape of the macrophages to a more spherical conformation rather than the amoeba-like state they assume on the dish




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