Jump to content

  • Log in with Facebook Log in with Twitter Log in with Windows Live Log In with Google      Sign In   
  • Create Account

Submit your paper to J Biol Methods today!
Photo
- - - - -

How does Mfold work??


  • Please log in to reply
1 reply to this topic

#1 Penguin

Penguin

    Enthusiast

  • Active Members
  • PipPipPipPipPip
  • 64 posts
1
Neutral

Posted 25 November 2010 - 04:11 AM

Hi all!

I have used Mfold to predict structures for some RNA molecules. The info on the Mfold website says that it uses energy-minimising algorithms to calculate possible RNA structures. So does this mean that only the most energetically favorable structures are plotted i.e. pair up G-C first? The output also gives deltaG values - so is this the amount of energy released upon the RNA folding?? What is more energetically favorable, a higher negative number e.g. deltaG = -13.6 or a lower negative number e.g. deltaG = -7.4??

Thanks!
P

#2 DELETEMYACCOUNTPLEASE

DELETEMYACCOUNTPLEASE

    Y U NOT DELETE MY ACCOUNT?

  • Active Members
  • PipPipPipPipPip
  • 58 posts
1
Neutral

Posted 26 November 2010 - 04:25 AM

http://nar.oxfordjou...31/13/3406.long should answer your questions.
http://en.wikipedia....bbs_free_energy just for fun.




Home - About - Terms of Service - Privacy - Contact Us

©1999-2013 Protocol Online, All rights reserved.