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MDA-MB-231: Triple negative or basal like breast cancer?


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#1 kitsonliew

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Posted 24 November 2010 - 12:28 AM

Hi all,

I am unsure whether MDA-MB-231 cell line belongs to which group. Is it triple negative breast cancer cell line or basal like breast cancer cell line? There are numerous number of papers pointing MDA-MB-231 belonged to the first group and simultaneously, MDA-MB-231 has also been widely reported as basal like breast cancer too.

Though both types of breast cancer are highly similar in terms of their ER/PR/HER2 status, it has to be noted there are more and more papers published saying the overlapping in terms of their character is not tantamount to absolute similarity.

Thus, I hope you all can enlighten me on the actual category of MDA-MB-231. Triple negative or basal like? It is even more helpful if you can provide me the link that proves this cell line is belonged to a particular group.

Thank you very much for your kind attention and time

Cheers,

Kitson

#2 shamash119

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Posted 18 January 2012 - 06:33 PM

MB-231 is both basal and triple negative.




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