Jump to content

  • Log in with Facebook Log in with Twitter Log in with Windows Live Log In with Google      Sign In   
  • Create Account

Submit your paper to J Biol Methods today!
Photo
- - - - -

Non sense mutation


  • Please log in to reply
1 reply to this topic

#1 marou

marou

    member

  • Members
  • Pip
  • 3 posts
0
Neutral

Posted 10 November 2010 - 10:28 PM

Hi
We tried to confirm the function of a gene having a nonsense mutation in the first exon. We did an insertional mutation in exon 2 and exon 4. The result that we find a wild type phenotype!
NB: The gene has 2 domains, one in the 1st exon, the other in the 2nd, 3rd and 4th exon.
Does the position of mutation has an effect on the phenotype?
Or does the nonsense mutation has no effect? if yes how could that happen? :blink:

Thank you for your help

#2 bob1

bob1

    Thelymitra pulchella

  • Global Moderators
  • PipPipPipPipPipPipPipPipPipPip
  • 5,506 posts
370
Excellent

Posted 11 November 2010 - 04:52 PM

Tertiary structure affected?




Home - About - Terms of Service - Privacy - Contact Us

©1999-2013 Protocol Online, All rights reserved.