What about an assay to discover which splicing factors bind to certain RNAs? Can you make a bead with a specific RNA on it, then mix a nuclear lysate with it, run a gel, cut the band, mass spec, and find out which proteins bind to your specific RNA of interest?
How does one make the bead with RNA on it? Is there a kit ffor that?
Submit your paper to J Biol Methods today!
RNA and beads!
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