oscillating effect after drug administration
Posted 11 September 2010 - 12:57 AM
Do you know any example of a single dose inhibitor which results in an oscillating effect of a biological response?
Posted 13 October 2010 - 10:02 AM
I got a paper this year in which I describe oscillations of receptor activity (ER) in response to continuous stimulation with different ligands (for 21 days). It is not exactly 'single dose' as you ask, but it is interesting as it comes out that such oscillations are somehow predictive of the drug structure. Here the pubmed link and a summary in my blog. Get in touch if you want to know more about it. Regards
Posted 10 November 2011 - 03:24 AM