1 reply to this topic

[Mr. Naive]

Hello friends,

I am wondering if there is any tool to functionally classify a set of differentially expressed miRNA. For example ranking the pathways that are effected by these set of miRNA in mouse. I know we can do a functional classification of the predicted target genes. But this makes things more non specific. So i want to just see what that set of differentially expressed miRNA directly means.  Please throw some light.

Thanks,
Anil.

[pcrman]

So far no effect has been made to functionally classify miRNA as the Gene Ontology project. Regardless, several miRNAs or clusters of miRNA have well documented function by the literature. You need to manually assign function to your miRNA of interest to see clustering of miRNA make sense functionally.