3 replies to this topic

[zodiac1505]

Does anyone know whether NOD mouse strain is less susceptible to S.aureus infection than C57BL/6 or BALB/c?

[doxorubicin]

This paper seems to compare c57 mice to NOD mice using one infection model:

http://diabetes.diab...54/10/2904.full

This paper compares various genetic backgrounds using another infection model:

http://jmm.sgmjourna...rint/48/11/1005

As does this one:

http://www3.intersci...001267/PDFSTART

[zodiac1505]

doxorubicin, on Jul 5 2010, 04:45 AM, said:

This paper seems to compare c57 mice to NOD mice using one infection model:

http://diabetes.diab...54/10/2904.full

This paper compares various genetic backgrounds using another infection model:

http://jmm.sgmjourna...rint/48/11/1005

As does this one:

http://www3.intersci...001267/PDFSTART

I found the first paper 3 days back and already read it. I think that's the most relevant to my question. We failed to observe an effect reported in the B6 mice in our NOD mice. I just wanted to know whether the reason may be that NOD mice have less susceptibility. But from the first paper I get the idea that they are as susceptible though it is not the same infection model nor the same S. aureus strain   So still no answer.

[pito]

zodiac1505, on Jul 5 2010, 04:58 PM, said:

doxorubicin, on Jul 5 2010, 04:45 AM, said:

This paper seems to compare c57 mice to NOD mice using one infection model:

http://diabetes.diab...54/10/2904.full

This paper compares various genetic backgrounds using another infection model:

http://jmm.sgmjourna...rint/48/11/1005

As does this one:

http://www3.intersci...001267/PDFSTART

I found the first paper 3 days back and already read it. I think that's the most relevant to my question. We failed to observe an effect reported in the B6 mice in our NOD mice. I just wanted to know whether the reason may be that NOD mice have less susceptibility. But from the first paper I get the idea that they are as susceptible though it is not the same infection model nor the same S. aureus strain   So still no answer.

Maybe you can contact the autors