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S. aureus susceptibility of different mouse trains


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#1 zodiac1505

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Posted 02 July 2010 - 04:26 AM

Does anyone know whether NOD mouse strain is less susceptible to S.aureus infection than C57BL/6 or BALB/c?

#2 doxorubicin

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Posted 04 July 2010 - 06:45 PM

This paper seems to compare c57 mice to NOD mice using one infection model:

http://diabetes.diab...54/10/2904.full

This paper compares various genetic backgrounds using another infection model:

http://jmm.sgmjourna...rint/48/11/1005

As does this one:

http://www3.intersci...001267/PDFSTART

#3 zodiac1505

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Posted 05 July 2010 - 06:58 AM

This paper seems to compare c57 mice to NOD mice using one infection model:

http://diabetes.diab...54/10/2904.full

This paper compares various genetic backgrounds using another infection model:

http://jmm.sgmjourna...rint/48/11/1005

As does this one:

http://www3.intersci...001267/PDFSTART


;)

I found the first paper 3 days back and already read it. I think that's the most relevant to my question. We failed to observe an effect reported in the B6 mice in our NOD mice. I just wanted to know whether the reason may be that NOD mice have less susceptibility. But from the first paper I get the idea that they are as susceptible though it is not the same infection model nor the same S. aureus strain :lol: So still no answer.

#4 pito

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Posted 06 July 2010 - 09:32 AM

This paper seems to compare c57 mice to NOD mice using one infection model:

http://diabetes.diab...54/10/2904.full

This paper compares various genetic backgrounds using another infection model:

http://jmm.sgmjourna...rint/48/11/1005

As does this one:

http://www3.intersci...001267/PDFSTART


;)

I found the first paper 3 days back and already read it. I think that's the most relevant to my question. We failed to observe an effect reported in the B6 mice in our NOD mice. I just wanted to know whether the reason may be that NOD mice have less susceptibility. But from the first paper I get the idea that they are as susceptible though it is not the same infection model nor the same S. aureus strain :D So still no answer.



Maybe you can contact the autors

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