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Where is the future of the proteomics?


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#1 parado

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Posted 14 June 2010 - 06:43 AM

this guy want to get a phd in this field.... but he feel lost ...

#2 parado

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Posted 14 June 2010 - 06:48 AM

still focus on the differential expression of proteins between CK and TR
or turn to PTM?
or just wait for the breakthrough in MS or other technics?



this guy want to get a phd in this field.... but he feel lost ...



#3 Inmost sun

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Posted 14 June 2010 - 02:03 PM

still focus on the differential expression of proteins between CK and TR
or turn to PTM?
or just wait for the breakthrough in MS or other technics?



this guy want to get a phd in this field.... but he feel lost ...


PTM is clear, what do you mean by CK and TR;

a combination of proteomics of differentiation-dependent expression and PTM is exciting;

one can always wait for better equipment and techniques but competitors rarely wait...

#4 Adrian K

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Posted 14 June 2010 - 03:42 PM

PTM? CK? TR?

Whats all this means?
:huh:
Expecting the world to treat you fairly because you are a good person is like expecting the lion not to attack you because you are a vegetarian.

..."best of our knowledge, as far as we know this had never been reported before, though I can't possible read all the published journals on earth, but by perform thorough search in google, the keywords did not match any documents"...

"what doesn't kill you, makes you stronger"---Goddess Casandra reminds me to be strong

"It's all just DNA. Do it."---phage434

#5 parado

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Posted 14 June 2010 - 06:41 PM

still focus on the differential expression of proteins between CK and TR
or turn to PTM?
or just wait for the breakthrough in MS or other technics?



this guy want to get a phd in this field.... but he feel lost ...


PTM is clear, what do you mean by CK and TR;

a combination of proteomics of differentiation-dependent expression and PTM is exciting;

one can always wait for better equipment and techniques but competitors rarely wait...



CK means control and TR means treatment. this is my habit to say so but may be wrong, so sorry.

i study peanut. i mean study the difference in protein expression between one group of peanut grow under normal condition and the other group under some stress treatment, and then can the mechanism of the stress resistant be discovered?

redulator protein rarely appear on the 2-D gel as a visible spot, and another thing the protein is always derived from a complex heterogeneous cells. the state of the protein modification is different at different location even in a sigle cell. that's why i think some breakthough should be come to overcome this problem .


to Adrian, PTM is post-translation-modification, such as phosphorylation, glycation, acylation, etc. PTMs are been taken for granted as a hotspot for the next several decades.

Edited by parado, 14 June 2010 - 06:43 PM.


#6 Adrian K

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Posted 15 June 2010 - 08:45 AM

Hi Parado,
Thanks for your enlightenment. Yes, I do agree there are lots of potential in proteomics. I'm also wish to learn in this field if there is a chance for me.
:)
Expecting the world to treat you fairly because you are a good person is like expecting the lion not to attack you because you are a vegetarian.

..."best of our knowledge, as far as we know this had never been reported before, though I can't possible read all the published journals on earth, but by perform thorough search in google, the keywords did not match any documents"...

"what doesn't kill you, makes you stronger"---Goddess Casandra reminds me to be strong

"It's all just DNA. Do it."---phage434




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