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CMV promoter


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#1 new2science

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Posted 23 May 2010 - 10:16 PM

Hi,

Can anyone help me and tell me what is the significance of using a CMV promotor in a vector versus a different type of promotor? And what does CMV stand for?

Thanks.

#2 leelee

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Posted 23 May 2010 - 11:28 PM

CMV stands for cytomegalovirus.
The CMV promoter is used because it is a very strong promoter, ie high levels of constitutive gene expression.
Also, it is effective in a broad range of cell types.

#3 new2science

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Posted 24 May 2010 - 11:53 AM

View Postleelee, on May 24 2010, 02:28 AM, said:

CMV stands for cytomegalovirus.
The CMV promoter is used because it is a very strong promoter, ie high levels of constitutive gene expression.
Also, it is effective in a broad range of cell types.


Thanks for the help!





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