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can someone list some proteasome inhibitors?


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4 replies to this topic

#1 yulang

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Posted 19 May 2010 - 06:00 AM

hi guys:
recently i have a experiment about detecting the ubiquitiantion protein in dendritic cell. but in my lab, there are nobody to do this. as a newer, i cannot do it by myself. can someone do a fever. thank you very much.

if there are some information about proteasome inhibitors, i will be lucky!
best wish!!

#2 Dr Teeth

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Posted 19 May 2010 - 06:03 AM

hi guys:
recently i have a experiment about detecting the ubiquitiantion protein in dendritic cell. but in my lab, there are nobody to do this. as a newer, i cannot do it by myself. can someone do a fever. thank you very much.

if there are some information about proteasome inhibitors, i will be lucky!
best wish!!


MG-132 is a commonly used 26S-proteasome inhibitor.

Science is simply common sense at its best that is rigidly accurate in observation and merciless to fallacy in logic.
Thomas Henry Huxley

#3 mdfenko

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Posted 19 May 2010 - 06:54 AM

there are a few listed at this wikipedia page.
talent does what it can
genius does what it must
i do what i get paid to do

#4 Another Jake

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Posted 19 May 2010 - 08:00 AM

Lactacystin costs a lot more than MG132, but is also more effective and specific.
I once used an even better one called Velcade, but it was extraordinarily expensive.

#5 yulang

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Posted 19 May 2010 - 08:36 PM

thanks for your replies! i am very appreciated. but the question is my cell line-dendritic cell. i found that some proteasome inhibitors(MG132) can influence the cell line (e.g:promote the cell appotosis). so i want to know if there are proteasome inhibitor having slight influence on dendritic cell.
and i will do CO-IP about ubiquitiate protein. does anybody have some protocol about that?
thank you very much.




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