I'm a newbie in this Molecular Biology as well as our forum, i mean this forum. I study about this subject "DNA damgade and repair" and my group need my performance . I need to explain 2 problems to them, they seem to be a general topic but i can not find much information about them. Could anyone help me some idea to answer those questions ? or show me some site could travel to find more information ?
1: the structural characteristics that make the translesion DNA synthesis (TDS) polymerases move "trans-lesion"
2: The in vivo and in vitro assays to study the functions of stress response factors for DNA damage
3: To make example , I need 5 diseases that are caused by defects in homologous recombination, if you could plz state the genetic abnormalities and clinical manisfestations of each.
Thank you very much for helping me this time. (and more many times , hihihi ).
Edited by Mangacoco, 27 April 2010 - 05:11 AM.