promoter methylation data analysis
Posted 22 April 2010 - 09:57 AM
Posted 07 October 2012 - 10:34 AM
I typed in MATLAB on the search engine and bumped on your post.
I am taking a matlab beginners' course and would like to know how you managed to use matlab on your methylation data. In our lab people use matlab to do image analysis only and was wondering how I can apply it to my methylation data. I used Rotor-Gene for a High Resolution Melt (HRM) analysis to determine percentages of methylation levels of my samples. Did you end up using matlab or did you find another way to deal with your data. I would be grateful if you could give me some advice.
Many thanks in advance,
Posted 01 November 2012 - 09:37 PM
Posted 26 August 2013 - 06:05 AM
If you want to analyse multiple CpG sites in one test its best to use mixed models to handle the correlation structure in the data (adjacent site may be highly correlated).
If you are new to statistics and genomics definetily consult with a statistician.