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Dimethyl Sulfate (DMS) as carrier in cell cultures


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#1 Kirstenf

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Posted 29 March 2010 - 01:59 AM

Hi
I have to resolve cyclophosphamid for cell culture testing. According to the manufactor the drug is not stable in aueous solution and recommends solution in Dimethyl Sulfate (DMS). It's an aŠkylating agent and highly toxic.

Has anyone got experience with using DMS as carrier? What would be an appropriate concentration of the carrier?

Thanks

Kirsten

Department of Haematology
Aalborg Hospital
Denmark

#2 Kirstenf

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Posted 29 March 2010 - 02:51 AM

I just talked to the manufactur. It's a mistake in their data sheet. It's DMSO - which makes more sense.

Best regards

Kirsten




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