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[TracyDuke]

We found a transcription factor being reduced at protein level up DNA damage but not changed at mRNA level. So the protein might be reduced by degradation. I wonder what reagents or drugs can be used to block protein degradation in general so that I can treat my cells with it along with DNA damage to see if the protein level can be maintained or less reduced.

[bob1]

MG132 will block the 18s proteasome, but there are more proteases than just that in cells.