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How can I inhibit apoptosis without use z-VAD?(in u87MG cells)..


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#1 autophagator

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Posted 25 February 2010 - 04:53 AM

Hi everybody.
We would like inhibit apoptosis in U87MG celular line to "clean" the experiment of this mechanism of death. But, the pancaspase inhibitor z-VAD is to many toxic to this cells when the experiment prolongs on time. I heard that Sodium Orthovanadate can inhibit apoptosis, but in some papers say the opositeĦĦ.
So, anybody knows or suggest other compound that inhibit apoptosis.

Thanks a lot in advance.





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