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macrophage transformation


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#1 clutz

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Posted 21 February 2010 - 06:59 AM

Does anyone tried to transform fresh macrophages to obtain a cell line with certain MHC haplotype? Would they retain their functions?
Thanks

#2 bob1

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Posted 21 February 2010 - 03:56 PM

It can be done.  They may or may not retain all functions you see in the non-transformed, it depends on how altered they are by the transformation.




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