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Bone marrow transplant


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#1 miss montana

miss montana

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Posted 10 February 2010 - 03:34 PM

Hi Everyone,

I would like to do a bone marrow transplant experiment. However, I only have access to male donors and my recipients will be a mixed population of both males and females. I was once told that using male bone marrow to reconstitute a female mouse wouldn't work because of the Y chromosome. The recipients will be lethally irradiated prior to the transplant, so I don't understand why this would be an issue. Is this really the case? (I should also mention that the mice are congenic.)


Thanks!

Edited by miss montana, 10 February 2010 - 03:39 PM.


#2 nikoletta

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Posted 12 February 2010 - 07:36 AM

it would be fine. transgender transplantation is a standard procedure, and a really usefull one. :)




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