1 reply to this topic

[miss montana]

Hi Everyone,

I would like to do a bone marrow transplant experiment.  However, I only have access to male donors and my recipients will be a mixed population of both males and females.  I was once told that using male bone marrow to reconstitute a female mouse wouldn't work because of the Y chromosome.  The recipients will be lethally irradiated prior to the transplant, so I don't understand why this would be an issue.  Is this really the case?  (I should also mention that the mice are congenic.)


Thanks!

Edited by miss montana, 10 February 2010 - 03:39 PM.

[nikoletta]

it would be fine. transgender transplantation is a standard procedure, and a really usefull one.