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Virus envelope


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#1 Psedonyme

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Posted 26 January 2010 - 07:30 AM

Hi everyone!

I'm currently working on an enveloped virus.
I would like to know if anyone has knowledge on a technique to eliminate virus envelope, keeping capsid intact.
My aim is to obtain a core population, after purification on sucrose gradients.
I search for articles on that subject, but it's apararently not a current experiment. I may try detergent such as Triton, but i'm not sure it will let the capsid intact.

Thanks in advance for your opinion, and sorry for my english

Psedonyme

#2 Another Jake

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Posted 05 May 2010 - 11:22 AM

Which virus?
There is tons of literature out there on stripping virus envelopes (for example, with NP40 and various amounts of salts).




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