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metabolic activation HepG2 and primary hepatocytes

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#1 bcsein



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Posted 23 November 2009 - 05:55 AM

Hello, I would like to know if the common method to check if a compound needs metabolic activation is getting the IC50 in HepG2 and primary hepatocytes and comparing . I would like to know which other methods are used for this.
Thank you very much

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