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A databse linking SNPs to functional consequences?


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#1 andy.dods6

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Posted 25 September 2009 - 08:04 AM

What I am looking for is a database, where i enter a protein name/accession code etc. and out will pop a list of known amino acid variants as a result of SNPs, AND any causative consequences of these SNPs.

EG.

INPUT - ENZYME A

OUTPUT

E134V - 30% decrease in enzyme activity
E199X - No activity decrease
N455X - total loss of enzyme activity


Obviously this is a very general query and any sort of database which could be mined would be of use.

Cheers

#2 bob1

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Posted 25 September 2009 - 02:49 PM

Try the Nucleic Acids Research online moleculr biology database collection: Here

#3 andy.dods6

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Posted 26 September 2009 - 05:24 AM

Try the Nucleic Acids Research online moleculr biology database collection: Here



A fantastic resource, thanks very much.

F-SNP

http://compbio.cs.queensu.ca/F-SNP/

seems to be what I am after.

Thanks again




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