2 replies to this topic

[andy.dods6]

What I am looking for is a database, where i enter a protein name/accession code etc. and out will pop a list of known amino acid variants as a result of SNPs, AND any causative consequences of these SNPs.

EG.

INPUT - ENZYME A

OUTPUT

E134V - 30% decrease in enzyme activity
E199X - No activity decrease
N455X - total loss of enzyme activity


Obviously this is a very general query and any sort of database which could be mined would be of use.

Cheers

[bob1]

Try the Nucleic Acids Research online moleculr biology database collection: Here

[andy.dods6]

bob1, on Sep 25 2009, 02:49 PM, said:

Try the Nucleic Acids Research online moleculr biology database collection: Here

A fantastic resource, thanks very much.

F-SNP

http://compbio.cs.queensu.ca/F-SNP/

seems to be what I am after.

Thanks again