can we use human anti C3 (complement protein) antibody against mouse C3? i have read that human C3 and mouse C3 have 77% homology.
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#1
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Posted 03 September 2009 - 09:57 PM
hi all
can we use human anti C3 (complement protein) antibody against mouse C3? i have read that human C3 and mouse C3 have 77% homology.
can we use human anti C3 (complement protein) antibody against mouse C3? i have read that human C3 and mouse C3 have 77% homology.
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#2
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Posted 04 September 2009 - 03:51 AM
ujla80, on Sep 4 2009, 06:57 AM, said:
hi all
can we use human anti C3 (complement protein) antibody against mouse C3? i have read that human C3 and mouse C3 have 77% homology.
can we use human anti C3 (complement protein) antibody against mouse C3? i have read that human C3 and mouse C3 have 77% homology.
Is your antibody monoclonal or polyclonal? If it is monoclonal it will only cross-react if the region to which the human antibody was raised is identical in the mouse protein. If it's a commercial antibody then the product details will tell you with which species it cross-reacts,
P
