determining incorrectly spliced transcripts
Posted 27 April 2002 - 06:48 AM
Posted 30 April 2002 - 01:04 AM
Hope this helps,
Posted 03 May 2002 - 06:13 AM
Posted 03 May 2002 - 06:53 AM
Posted 08 May 2002 - 10:33 PM
It seems that the nuclear pre-mRNA splicing could impinge on three major aspects of gene expression: the production of differents protein isoforms, the kinetics of expression by altering the duration of the processing and the level of final product, though the efficiency of processing. I've read that src could act on pre-mRNA processing of TNFB by slowing down splicing and by acting on the export of partially spliced transcripts. For more information see Neel et al, current biology 1995,5(4):413-422.