can anybody help me please, which one of these methods is the most efficient one to showing an ínteraction bwn 2 proteins?
* ??or do you have a better idea?
Immunohistochemically, we could show the colocalization between 2 membranproteins. The question is now: do these proteins interact with each other directly and therefore we get a colocalisationsignal or they are just in close neighbourhood of each other and due to this adjacency we get a signal.
which method have I to use in order to be able to prove the colocalisation?