0
Tomorrow = a new day
11 August 2011
First off I would like to start my first blog stating: this summer has been the most helpful (academic wise) than any other. I'm conducting undergraduate research in a virology laboratory at UCI. Its my first time exposed to the life of applied science and I am really enjoying it. My time is spent learning assay's, refining my techniques and understanding the mechanisms at work.
I would like to start this blog by informing reader as to what my lab is doing;
The topic of investigation is a focus on the antiviral activity of human antibodies and chimeric molecules directed against the membrane phospholipid, phosphatidylserine. These antibodies are manufactured by a drug co. The chief objective is to propagate and grow viruses in their respective host mammalian cell lines and to conduct viral inactivation assays using the drug co's anti phospholipid reagents. The specific hypothesis which is being tested originates from the nature of phosphatidylserine. Phosphatidylserine is normally limited to the inner leflet of the plasma membrane but is reallocated to the outer surface during cellular injury, apoptosis or cellular activation. Viral infection often induces apoptosis which exposes phosphatidylserine on the surface of infected cells. The hypothesis is that one or more of the drug co's anti-PS antibodies or chimeric molecules will exhibit significant antiviral activity against one or more of the viruses that the lab is studying.
I would like to start this blog by informing reader as to what my lab is doing;
The topic of investigation is a focus on the antiviral activity of human antibodies and chimeric molecules directed against the membrane phospholipid, phosphatidylserine. These antibodies are manufactured by a drug co. The chief objective is to propagate and grow viruses in their respective host mammalian cell lines and to conduct viral inactivation assays using the drug co's anti phospholipid reagents. The specific hypothesis which is being tested originates from the nature of phosphatidylserine. Phosphatidylserine is normally limited to the inner leflet of the plasma membrane but is reallocated to the outer surface during cellular injury, apoptosis or cellular activation. Viral infection often induces apoptosis which exposes phosphatidylserine on the surface of infected cells. The hypothesis is that one or more of the drug co's anti-PS antibodies or chimeric molecules will exhibit significant antiviral activity against one or more of the viruses that the lab is studying.
