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An Introduction to the Genetics and Molecular Biology of the
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An Introduction to the Genetics and Molecular Biology of the
Yeast Saccharomyces cerevisiae

Fred Sherman

Department of Biochemistry and Biophysics
University of Rochester Medical School, Rochester, NY 14642


Modified from: F. Sherman, Yeast genetics.
The Encyclopedia of Molecular Biology and Molecular Medicine,
pp. 302-325, Vol. 6. Edited by R. A. Meyers, VCH Pub., Weinheim, Germany,1997.

The yeast Saccharomyces cerevisiae is clearly the most ideal eukaryotic microorganism for biological studies. The "awesome power of yeast genetics" has become legendary and is the envy of those who work with higher eukaryotes. The complete sequence of its genome has proved to be extremely useful as a reference towards the sequences of human and other higher eukaryotic genes. Furthermore, the ease of genetic manipulation of yeast allows its use for conveniently analyzing and functionally dissecting gene products from other eukaryotes.

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