BioProduct : Chemicals & Compounds : MS-275
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Product Name MS-275
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Product Description MS-275(Entinostat) is synthetic benzamide derivative with potential antineoplastic activity. This agent preferentially inhibits HDAC1 (IC50=300 nM) over HDAC3 (IC50=8 µM) and has no inhibitory activity towards HDAC8 (IC50>100 µM). This agent appears to exert dose-dependent effects in human leukemia cells at low drug concentrations in human prostate cancer cell lines. MS-275 exerted growth arrest in PC-3 and LNCaP cells, and induced cell death in DU-145 cells.
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Price $88
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Vendor Information Selleck
2626 South Loop West, Suite 225, Houston, TX 77054 USA